Avian coccidiosis remains one of the most widespread, costly, and significant diseases in commercial poultry farming. The large capacity of hatcheries, their automation, and the advantage of individual dosing make in-ovo vaccination ideal in current poultry production conditions.

In this study, a field trial was conducted to assess the safety and efficacy of in-ovo coadministration of a commercial immunocomplex vaccine against infectious bursitis applied together with a new in-ovo vaccine against avian coccidiosis, compared to in-ovo administration of this same Infectious Bursitis Disease vaccine followed by thick-droplet spray vaccination of another coccidiosis vaccine.

The objective of this multicentre, randomized, double-blind, double-simulation, positive control field trial was to evaluate the safety and efficacy of EVANOVO® when administered under field conditions in a commercial hatchery.