RHINISENG^® is a vaccine against progressive (PAR) and non-progressive atrophic rhinitis (NPAR) indicated for pregnant sows and gilts to passively protect their offspring. The RHINISENG^® recommended vaccination scheme includes a basic vaccination scheme (vaccination 8-6 weeks before farrowing and revaccination 4-3 weeks before farrowing) and a booster dose (4-3 weeks before the subsequent farrowing). This study evaluated the vaccine pre-clinical efficacy and the duration of immunity for active immunization of the sows.