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Rabbit haemorrhagic disease (RHD)

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Rabbit haemorrhagic disease (RHD)

AETIOLOGY:

Calicivirus, a haemagglutinating RNA virus, very diffusible and stable in the environment.

 

TRANSMISSION:

  • Direct: secretions and excretions.

     
  • Indirect: fomites and vectors.

 

CLINICAL SIGNS: 

High mortality. Sudden death in its hyperacute form. Increased temperature and respiratory rate, and sometimes epistaxis and nervous disorders in the acute and subacute forms of the disease. 

 

LESIONS: 

Hepatic necrosis, congestion and haemorrhage in multiple organs: trachea, spleen, thymus and lungs.

 

DIAGNOSIS:

  • Identification of the causative agent: HA, electron microscopy, sandwich ELISA, PCR and Western Blot. 

     
  • Serology: IHA and ELISA.  

 

TREATMENT, PREVENTION AND CONTROL:

Biosecurity measures. Inactivated vaccines adjuvanted with mineral oil or aluminium hydroxide.