Bordetella bronchiseptica is a widespread, highly infectious cause of respiratory disease in swine. Disease varies from mild, subclinical infections to severe pneumonia or atrophic rhinitis. B. bronchiseptica also exacerbates viral respiratory infection and enhances colonization and/or disease with other bacterial pathogens.

Vaccination improves clinical health and performance, but elimination of B. bronchiseptica can be challenging due to the difficulty of fully clearing the bacterium using vaccines and antibiotics.