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A new attenuated IBR live vaccine with double genetic deletion gE-tk- is efficacious in front of experimental BoHV-1 infections, even in presence of maternally derived antibodies

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Moreno, A.; Casado, C.; Roca, M.; Creixans, O.

IBR (Infectious Bovine Rhinotracheitis) eradication programs in the EU are based mainly on a DIVA (Differentiation of Infected from Vaccinated Animals) strategy by using marker vaccines. So far, all these IBR marker vaccines were based on single deleted BoHV-1 gE- strains: Bovine HerpesVirus-1 strains lacking glycoprotein E.

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