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4. Geographical distribution

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Two genotypes have been recognised (type 1 or European, and type 2 or North-American); type 1 is the predominant genotype in Europe while type 2 is the most present in America and Asia. Within type 1, at least 4 different subtypes have been reported; subtype I is predominant in Western Europe whereas subtypes II, III and IV have been isolated only in countries eastwards of Poland until now. Regarding type 2, two clades have been described.

Nevertheless, both type 1 and 2 are disseminated worldwide; they can be found in almost all pig-producing countries, with the exception of Australia, New Zealand, Scandinavia, Switzerland and some South American countries that are PRRS virus-free.

The highly-pathogenic PRRS virus which emerged in China belongs to type 2. It rapidly spread throughout Asia. Nowadays, it can be found in East, South and North Asia: Bhutan, Cambodia, China, Indonesia, Laos, Malaysia, Myanmar, the Philippines, Russia, Singapore, Vietnam, etc. (World Organisation for Animal Health; World Animal Health Information Database Interface; OIE 2013).

 

As can be deduced from the PRRS virus global distribution map, the risk of intercontinental transmission of any strain, including the highly pathogenic strains detected in Asia, is extremely real. Also, as has recently been observed in Chile, the re-introduction of PRRS virus in a PRRS virus-free country can be devastating.

 

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REFERENCES:

  • Baron T, Albina E, Leforban Y, Madec F, Guilmoto H, Plana Duran J, Vannier P. Report on the first outbreaks of the porcine reproductive and respiratory syndrome (PRRS) in France. Diagnosis and viral isolation. Ann Rech Vet. 1992, 23:161-6.
  • Benfield DA, Nelson E, Collins JE, Harris L, Hennings JC, Shaw DP, Goyal SM, McCullough S, Morrison RB, Joo HS, Gorcyca D, Chladek D. Characterization of swine infertility and respiratory syndrome (SIRS) virus (isolate ATCC VR-2332). J Vet Diagn Invest. 1992. 4, 127-133.
  • Benfield D, Nelson J, Rossow K, Nelson C, Steffen M, Rowland R. Diagnosis of persistent or prolonged porcine reproductive and respiratory syndrome virus infections Vet Res. 2000, 31:71.
  • Blaha T. The ”colorful” epidemiology of PRRS. Vet Res BioMed Central. 2000, 31:77-83.
  • Carman S, Sanford SE, Dea S. Assessment of seropositivity to porcine reproductive and respiratory syndrome (PRRS) virus in swine herds in Ontario--1978 to 1982. Can Vet J. 1995, 36:776-7.
  • Collins JE, Benfield DA, Christianson WT, Harris L, Hennings JC, Shaw DP, Goyal SM, McCullough S, Morrison RB, Joo HS, et al. Isolation of swine infertility and respiratory syndrome virus (isolate ATCC VR-2332) in North America and experimental reproduction of the disease in gnotobiotic pigs. J Vet Diagn Invest. 1992, 4:117-26.
  • Delrue I, Van Gorp H, Van Doorsselaere J, Delputte PL, Nauwynck HJ. Susceptible cell lines for the production of porcine reproductive and respiratory syndrome virus by stable transfection of sialoadhesin and CD163. BMC Biotechnol. 2010, 29:10:48.
  • Díaz I, Darwich L, Pappaterra G, Pujols J, Mateu E. Different European-type vaccines against porcine reproductive and respiratory syndrome virus have different immunological properties and confer different protection to pigs. Virology. 2006, 351:249-59.
  • Duan X, Nauwynck HJ, Pensaert MB. Virus quantification and identification of cellular targets in the lungs and lymphoid tissues of pigs at different time intervals after inoculation with porcine reproductive and respiratory syndrome virus (PRRSV). Vet Microbiol. 1997, 56:9-19.
  • Forsberg R, Oleksiewicz MB, Petersen AM, Hein J, Bøtner A, Storgaard T. A molecular clock dates the common ancestor of European-type porcine reproductive and respiratory syndrome virus at more than 10 years before the emergence of disease. Virology. 2001, 289:174-9.
  • Gómez-Laguna J, Salguero FJ, Pallarés FJ, Carrasco L. Immunopathogenesis of porcine reproductive and respiratory syndrome in the respiratory tract of pigs. Vet J. 2013, 195:148-55.
  • He Q, Li Y, Zhou L, Ge X, Guo X, Yang H. Both Nsp1β and Nsp11 are responsible for differential TNF-α production induced by porcine reproductive and respiratory syndrome virus strains with different pathogenicity in vitro. Virus Res. 2015, 201:32-40.
  • Hill H. Overview and history of Mystery Swine Disease (swine infertility/respiratory syndrome). Proceedings of the Mystery Swine Disease Committee Meeting, Livestock Conversation Institute, Denver, CO. 1990, 29–31.
  • Hirose 0, Kudo H, Yoshizawa S, Hiroike T, Nakane T. Prevalence of porcine reproductive and respiratory syndrome virus in Chiba prefecture. J Jpn Vet Med Assoc. 1995, 48:650-3.
  • Holtkamp DJ, Kliebenstein JB, Neumann EJ, Zimmerman JJ, Rotto HF, Yoder TK, Wang C, Yeske PE, Mowrer CL and Haley CA. Assessment of the economic impact of porcine reproductive and respiratory syndrome virus on United States pork producers. J Swine Health Prod. 2013, 21:72-84.
  • Karniychuk UU, Nauwynck HJ. Quantitative changes of sialoadhesin and CD163 positive macrophages in the implantation sites and organs of porcine embryos/fetuses during gestation. Placenta. 2009, 30:497-500.
  • Karniychuk UU, Geldhof M, Vanhee M, Van Doorsselaere J, Saveleva TA, Nauwynck HJ. Pathogenesis and antigenic characterization of a new East European subtype 3 porcine reproductive and respiratory syndrome virus isolate. BMC Vet Res. 2010, 4:6:30.
  • Karniychuk UU, Nauwynck HJ. Pathogenesis and prevention of placental and transplacental porcine reproductive and respiratory syndrome virus infection. Vet Res. 2013, 44:95.
  • Keffaber KK. Reproductive failure of unknown etiology. AASP. 1989, 1: 2–10.
  • Lawson SR, Rossow KD, Collins JE, Benfield DA, Rowland RR. Porcine reproductive and respiratory syndrome virus infection of gnotobiotic pigs: sites of virus replication and co-localization with MAC-387 staining at 21 days post-infection. Virus Res. 1997, 51:105-13.
  • Leng X, Li Z, Xia M, Li X, Wang F, Wang W, Zhang X, Wu H. Mutations in the genome of the highly pathogenic porcine reproductive and respiratory syndrome virus potentially related to attenuation. Vet Microbiol. 2012, 157:50-60.
  • Li Y, Zhou L, Zhang J, Ge X, Zhou R, Zheng H, Geng G, Guo X, Yang H. Nsp9 and Nsp10 contribute to the fatal virulence of highly pathogenic porcine reproductive and respiratory syndrome virus emerging in China. PLoS Pathog. 2014, 10(7):e1004216.
  • Lindhaus W, Lindhaus B. Raetselhafte Schweinekrankheit. Prakt Tierarzt 1991, 5:423–5
  • Loula T. Mystery pig disease. Agri-practice. 1991, 12:23–34.
  • Loving CL, Brockmeier SL, Sacco RE. Differential type I interferon activation and susceptibility of dendritic cell populations to porcine arterivirus. Immunology. 2007, 120:217-29.
  • Lu W, Sun B, Mo J, Zeng X, Zhang G, Wang L, Zhou Q, Zhu L, Li Z, Xie Q, Bi Y, Ma J. Attenuation and immunogenicity of a live high pathogenic PRRSV vaccine candidate with a 32-amino acid deletion in the nsp2 protein. J Immunol Res. 2014, 2014:810523.
  • Lunney JK, Benfield DA, Rowland RR.Porcine reproductive and respiratory syndrome virus: an update on an emerging and re-emerging viral disease of swine. Virus Res. 2010, 154:1-6.
  • Mardassi H, Massie B, Dea S. Intracellular synthesis, processing, and transport of proteins encoded by ORFs 5 to 7 of porcine reproductive and respiratory syndrome virus. Virology. 1996, 221:98-112.
  • Martínez-Lobo FJ, Díez-Fuertes F, Segalés J, García-Artiga C, Simarro I, Castro JM, Prieto C. Comparative pathogenicity of type 1 and type 2 isolates of porcine reproductive and respiratory syndrome virus (PRRSV) in a young pig infection model. Vet Microbiol. 2011, 154:58-68.
  • Mateu E, Diaz I. The challenge of PRRS immunology. Vet J. 2008, 177:345-51.
  • Meng XJ, Paul PS, Halbur PG. Molecular cloning and nucleotide sequencing of the 3'-terminal genomic RNA of the porcine reproductive and respiratory syndrome virus. J Gen Virol. 1994, 75:1795-801.
  • Meng XJ, Paul PS, Halbur PG, Lum MA. Phylogenetic analyses of the putative M (ORF 6) and N (ORF 7) genes of porcine reproductive and respiratory syndrome virus (PRRSV): implication for the existence of two genotypes of PRRSV in the U.S.A. and Europe. Arch Virol. 1995, 140:745-55.
  • Meredith MJ. Review of porcine reproductive and respiratory syndrome. Pig Disease Information Centre, University of Cambridge, Cambridge, England. 1-24.
  • Meulenberg JJ, Hulst MM, de Meijer EJ, Moonen PL, den Besten A, de Kluyver EP, Wensvoort G, Moormann RJ. Lelystad virus, the causative agent of porcine epidemic abortion and respiratory syndrome (PEARS), is related to LDV and EAV. Virology. 1993, 192:62-72.
  • Meulenberg JJ, Hulst MM, de Meijer EJ, Moonen PL, den Besten A, de Kluyver EP, Wensvoort G, Moormann RJ. Lelystad virus belongs to a new virus family, comprising lactate dehydrogenase-elevating virus, equine arteritis virus, and simian hemorrhagic fever virus. Arch Virol Suppl. 1994, 9:441-8.
  • Meulenberg JJ, Petersen-den Besten A, De Kluyver EP, Moormann RJ, Schaaper WM, Wensvoort G. Characterization of proteins encoded by ORFs 2 to 7 of Lelystad virus. Virology. 1995, 206:155-63.
  • Murtaugh MP1, Elam MR, Kakach LT. Comparison of the structural protein coding sequences of the VR-2332 and Lelystad virus strains of the PRRS virus. Arch Virol. 1995, 140:1451-60.
  • Murtaugh MP, Stadejek T, Abrahante JE, Lam TT, Leung FC. The ever-expanding diversity of porcine reproductive and respiratory syndrome virus. Virus Res. 2010, 154:18-30.
  • Neumann EJ, Kliebenstein JB, Johnson CD, Mabry JW, Bush EJ, Seitzinger AH, Green AL, Zimmerman JJ. Assessment of the economic impact of porcine reproductive and respiratory syndrome on swine production in the United States. J Am Vet Med Assoc. 2005, 227:385-92.
  • Nieuwenhuis N, Duinhof TF, van Nes A. Economic analysis of outbreaks of porcine reproductive and respiratory syndrome virus in nine sow herds. Vet Rec. 2012, 170:225.
  • Ohlinger V.F., Pesch S., Bischoff C., History, occurrence, dynamics and current status of PRRS in Europe, Vet Res. 2000, 31: 86-87.
  • OIE. World Organisation for Animal Health; World Animal Health Information Database Interface; OIE 2013.
  • Pirtle EC, Beran GW. Stability of porcine reproductive and respiratory syndrome virus in the presence of fomites commonly found on farms. J Am Vet Med Assoc. 1996, 208:390-2. Plagemann PG. Porcine reproductive and respiratory syndrome virus: origin hypothesis. Emerg Infect Dis. 2003, 9:903-8.
  • Plagemann PG. Lactate dehydrogenase-elevating virus and related viruses. In: Fields Virology, 3rd ed. Ed. Fields BN, Knipe DM, Howley PM, et al. 1105-20.
  • Plana J, Vayreda M, Vilarrasa J, Bastons M, Rosell R, Martinez M, San Gabriel A, Pujols J, Badiola JL, Ramos JA, et al. Porcine epidemic abortion and respiratory syndrome (mystery swine disease). Isolation in Spain of the causative agent and experimental reproduction of the disease. Vet Microbiol. 1992, 33:203-11.
  • Shin JH, Kang YB, Kim YJ, Yeom SH, Kweon CH, Lee WY, Jean YH, Hwang EK, Rhee JC, An SH, Cho IS, Oh JS, Joo HS, Choi CS, Molitor TW. Sero-epidemiological studies on porcine reproductive and respiratory syndrome in Korea. I. Detection of indirect fluorescent antibodies. RDA J Agri Sci. 1993, 35: 572-6.
  • SIP Consultors. Repercusión económica del PRRS. Lleida, Spain. 2013.
  • Snijder EJ, Kikkert M, Fang Y. Arterivirus molecular biology and pathogenesis. J Gen Virol. 2013, 94:2141-63.
  • Thanawongnuwech R, Thacker EL, Halbur PG. Effect of Porcine reproductive and respiratory syndrome virus (PRRSV) (isolate ATCC VR-2385) infection on bactericidal activity of porcine pulmonary intravascular macrophages (PIMs): In vitro comparisons with pulmonary alveolar macrophages (PAMs). Vet Immunol Immunopathol. 1997, 59:323-335.
  • Tian K, Yu X, Zhao T, Feng Y, Cao Z, Wang C, Hu Y, Chen X, Hu D, Tian X, Liu D, Zhang S, Deng X, Ding Y, Yang L, Zhang Y, Xiao H, Qiao M, Wang B, Hou L, Wang X, Yang X, Kang L, Sun M, Jin P, Wang S, Kitamura Y, Yan J, Gao GF. Emergence of fatal PRRSV variants: unparalleled outbreaks of atypical PRRS in China and molecular dissection of the unique hallmark. PLoS One. 200, 2:e526.
  • Van der Linden IF, Voermans JJ, van der Linde-Bril EM, Bianchi AT, Steverink PJ. Virological kinetics and immunological responses to a porcine reproductive and respiratory syndrome virus infection of pigs at different ages. Vaccine. 2003, 21:1952-7.
  • Van Gorp H, Van Breedam W, Delputte PL, Nauwynck HJ. Sialoadhesin and CD163 join forces during entry of the porcine reproductive and respiratory syndrome virus. J Gen Virol. 2008, 89:2943-53.
  • Wang G, Song T, Yu Y, Liu Y, Shi W, Wang S, Rong F, Dong J, Liu H, Cai X, Zhou EM. Immune responses in piglets infected with highly pathogenic porcine reproductive and respiratory syndrome virus. Vet Immunol Immunopathol. 2011, 142:170-8.
  • Wensvoort G, Terpstra C, Pol JMA, Lask EA, Bloemraad M, de Kluyver EP, Kragten C, van Butten L, den Besten A, Wagenaar F, Broekhuijsen JM, Moonen PJM, Zetstra T, de Boer EA, Tibben AhJ, de Jong MF, van’r Veld P, Groenland GJR, van Gennep JA, Voets MTh, Verheijden JHM, Braamkamp J. Mystery swine disease in the Netherlands: the isolation of Lelystad virus. Vet Q. 1991, 13:121–30.
  • White M. Blue ear disease of pigs. Vet Rec. 1991, 128:574.
  • White M. The clinical signs and symptoms of “blue eared pig disease”. Pig Vet J. 1991, 28:62-8.
  • Yamane I, Kure K, Ishikawa H, Takagi M, Miyazaki A, Suzuki T, Shibahara T, Kubo M, Kobayashi H, Kokuho T, Tsunemitsu H. Estimation of economic loss due to porcine reproductive and respiratory syndrome in Japan.
  • Yun SI, Lee YM. Overview: Replication of porcine reproductive and respiratory syndrome virus. J Microbiol. 2013, 51:711-23.
  • Zhang Q, Yoo D. PRRS virus receptors and their role for pathogenesis. Vet Microbiol. 2015, 177:229-41.
  • Zimmerman J, Yoon K-J, Wills RW, Swenson SL. General overview of PRRSV: A perspective from the United States. Vet Microbiol. 1997, 55:187-96.
  • Zhou Z, Ni J, Cao Z, Han X, Xia Y, Zi Z, Ning K, Liu Q, Cai L, Qiu P, Deng X, Hu D, Zhang Q, Fan Y, Wu J, Wang L, Zhang M, Yu X, Zhai X, Tian K. The epidemic status and genetic diversity of 14 highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) isolates from China in 2009. Vet Microbiol. 2011, 150:257-69.
  • Zimmerman JJ, Benfield DA, Dee SA, Murtaugh MP, Stadejek T, Stevenson GW, Torremorell M. Porcine reproductive and respiratory syndrome virus (porcine arterivirus). In: 10th ed. Diseases of swine, Ed. Wiley-Blackwell. 2012, 31:463-86.
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